|
|
D-serine <=> pyruvate + NH3
|
4.3.1.15
diaminopropionate ammonia-lyase
4.3.1.18
D-serine ammonia-lyase
|
–
–
|
BK
|
|
BRENDA:
BR22833
KEGG:
R00221
MetaCyc:
DSERDEAM-RXN
SABIO-RK:
746
|
|
|
|
L-serine <=> D-serine
|
4.3.1.17
L-serine ammonia-lyase
5.1.1.1
alanine racemase
5.1.1.10
amino-acid racemase
5.1.1.18
serine racemase
|
–
–
–
–
|
BMK
|
|
BRENDA:
BR48732
KEGG:
R00589
MetaCyc:
5.1.1.18-RXN
SABIO-RK:
988
|
|
|
|
D-alanine + D-serine + ATP <=> H+ + D-Ala-D-Ser + phosphate + ADP
|
6.3.2.35
D-alanine---D-serine ligase
|
–
|
M
|
|
BRENDA:
BR49370
KEGG:
R09595
MetaCyc:
RXN-11299
|
|
|
|
D-phosphoserine + H2O <=> D-serine + phosphate
|
3.1.3.3
phosphoserine phosphatase
|
–
|
|
|
BRENDA:
BS446058
KEGG:
R02853
SABIO-RK:
2717
|
|
|
|
D-serine + H2O + O2 <=> Hydroxypyruvate + NH3 + H2O2
|
1.4.3.3
D-amino-acid oxidase
|
–
|
|
|
BRENDA:
BS259054
SABIO-RK:
7751
|
|
|
|
D-Ala-D-Ser + H2O <=> D-alanine + D-serine
|
3.4.13.22
D-Ala-D-Ala dipeptidase
|
–
|
|
|
BRENDA:
BS384509
SABIO-RK:
7269
|
|
|
|
D-serine + tetrahydrofolate <=> glycine + 5,10-methylenetetrahydrofolate + H2O
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS409177
SABIO-RK:
15181
|
|
|
|
D-serine + 2-amino-5-guanidinovalerate <=> D-lombricine + L-ornithine
|
not assigned
|
–
|
K
|
|
KEGG:
R02854
|
|
|
|
D-serine <=> 2-aminoacrylate + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15581
|
|
|
|
H+ + D-serine <=> H+ + D-serine
|
not assigned
|
–
|
|
|
MetaCyc:
RXN0-5130
|
|
|
|
D-serine <=> D-serine
|
not assigned
|
–
|
|
|
MetaCyc:
TRANS-RXN0-495
|
|
|
|
DL-phosphoserine + H2O <=> D-serine + phosphate
|
3.1.3.2
acid phosphatase
|
–
|
|
|
BRENDA:
BS393030
|
|
|
|
D-serine + benzaldehyde <=> 2-amino-3-hydroxy-2-hydroxymethyl-3-phenylpropanoic_acid
|
4.1.2.42
D-threonine aldolase
4.1.2.5
L-threonine aldolase
|
–
–
|
|
|
BRENDA:
BS445419
|
|
|
|
D-serine + H2O + FAD <=> Hydroxypyruvate + NH3 + FADH2
|
1.4.99.6
D-arginine dehydrogenase
|
–
|
|
|
BRENDA:
BS260555
|
|
|
|
D-serine + benzaldehyde + H2O <=> (2S,3S)-2-amino-3-hydroxy-2-(hydroxymethyl)-3-phenylpropanoic_acid + (2S,3R)-2-amino-3-hydroxy-2-(hydroxymethyl)-3-phenylpropanoic_acid
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455528
|
|
|
|
D-serine + H2O + 2,6-dichlorophenolindophenol <=> Hydroxypyruvate + NH3 + reduced_2,6-dichlorophenolindophenol
|
1.4.99.6
D-arginine dehydrogenase
|
–
|
|
|
BRENDA:
BS260518
|
|
|
|
phosphatidylcholine + D-serine <=> phosphatidylserine + choline
|
3.1.4.4
phospholipase D
|
–
|
|
|
BRENDA:
BS401647
|
|
|
|
L-Serinamide + H2O <=> D-serine + NH3
|
3.4.11.19
D-stereospecific aminopeptidase
|
–
|
|
|
BRENDA:
BS394391
|
|
|
|
N-carbamoyl-D-Ser + H2O <=> D-serine + NH3 + CO2
|
3.5.1.77
N-carbamoyl-D-amino-acid hydrolase
|
–
|
|
|
BRENDA:
BS17753
|
|
|
|
D-Ser-D-Ala + H2O <=> D-serine + D-alanine
|
3.4.13.22
D-Ala-D-Ala dipeptidase
|
–
|
|
|
BRENDA:
BS36685
|
|
|
|
acetyl-CoA + D-serine <=> CoA + N-acetyl-D-serine
|
2.3.1.36
D-amino-acid N-acetyltransferase
|
–
|
|
|
BRENDA:
BS320825
|
|
|
|
L-Leu-D-Ser + H2O <=> L-leucine + D-serine
|
3.4.13.19
membrane dipeptidase
|
–
|
|
|
BRENDA:
BS412280
|
|
|
|
D-serine + pyruvate <=> Hydroxypyruvate + D-alanine
|
2.6.1.21
D-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353674
|
|
|
|
D-Serine_amide + H2O <=> D-serine + NH3
|
3.4.11.19
D-stereospecific aminopeptidase
|
–
|
|
|
BRENDA:
BS361451
|
|
|
|
propionyl-CoA + D-serine <=> CoA + N-propionyl-D-serine
|
2.3.1.36
D-amino-acid N-acetyltransferase
|
–
|
|
|
BRENDA:
BS320835
|
|
|
|
D-serine + 2-oxoglutarate <=> Hydroxypyruvate + D-glutamate
|
2.6.1.21
D-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353649
|
|
|
|
tetrahydrofolate + hydroxymethylserine <=> 5,10-methylenetetrahydrofolate + D-serine + H2O
|
2.1.2.7
D-alanine 2-hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS320082
|
|
|
|
D-serine + ubiquinone + H2O <=> Hydroxypyruvate + NH3 + ubiquinol
|
1.4.5.1
D-amino acid dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS404905
|
|
|
|
D-serine + indole <=> L-tryptophan + H2O
|
4.1.99.1
tryptophanase
|
–
|
|
|
BRENDA:
BS409176
|
|
|
|
D-serine + H2O + NAD+ <=> Hydroxypyruvate + NH3 + NADH
|
1.4.1.1
alanine dehydrogenase
1.4.1.7
serine 2-dehydrogenase
|
–
–
|
|
|
BRENDA:
BS232304
|
|
|
|
D-serine + benzyl_[(2R)-1-oxopropan-2-yl]carbamate + H2O <=> (3S,4R)-4-[[(benzyloxy)carbonyl]amino]-3-hydroxy-2-(hydroxymethyl)-L-norvaline + (3R,4R)-4-[[(benzyloxy)carbonyl]amino]-3-hydroxy-2-(hydroxymethyl)-L-norvaline
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455531
|
|
|
|
D-serine + pentafluorobenzaldehyde + H2O <=> (2S,3S)-2-amino-3-hydroxy-2-(hydroxymethyl)-3-(pentafluorophenyl)propanoic_acid + (2S,3R)-2-amino-3-hydroxy-2-(hydroxymethyl)-3-(pentafluorophenyl)propanoic_acid
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455533
|
|
|
|
D-serine + benzyloxyacetaldehyde + H2O <=> (3R)-4-(benzyloxy)-2'',3-dihydroxy-L-isovaline + (3S)-4-(benzyloxy)-2'',3-dihydroxy-L-isovaline
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455520
|
|
|
|
docosahexanoylphosphatidylcholine + D-serine <=> docosahexanoylphosphatidylserine + choline
|
3.1.4.4
phospholipase D
|
–
|
|
|
BRENDA:
BS446916
|
|
|
|
D-serine + 4-(benzyloxy)butanal + H2O <=> (3S)-4-[[(benzyloxy)carbonyl]amino]-2'',3-dihydroxy-L-isovaline + (3S)-2'',3-dihydroxy-4-(3-phenylpropoxy)-L-isovaline
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455523
|
|
|
|
D-serine + 4-Chlorobenzaldehyde + H2O <=> (2S,3S)-2-amino-3-(4-chlorophenyl)-3-hydroxy-2-(hydroxymethyl)propanoic_acid + (2S,3R)-2-amino-3-(4-chlorophenyl)-3-hydroxy-2-(hydroxymethyl)propanoic_acid
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455524
|
|
|
|
D-serine + 3-Nitrobenzaldehyde <=> beta-(3-nitrophenyl)-alpha-hydroxymethyl-serine
|
4.1.2.42
D-threonine aldolase
4.1.2.5
L-threonine aldolase
|
–
–
|
|
|
BRENDA:
BS445418
|
|
|
|
D-serine + 2-Fluorobenzaldehyde + H2O <=> (2S,3S)-2-amino-3-(2-fluorophenyl)-3-hydroxy-2-(hydroxymethyl)propanoic_acid + (2S,3R)-2-amino-3-(2-fluorophenyl)-3-hydroxy-2-(hydroxymethyl)propanoic_acid
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455521
|
|
|
|
D-serine + phenoxyacetaldehyde + H2O <=> (3R)-2'',3-dihydroxy-4-phenoxy-L-isovaline + (3S)-2'',3-dihydroxy-4-phenoxy-L-isovaline
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455534
|
|
|
|
D-serine + 3-phenylpropanal + H2O <=> (3S)-3-hydroxy-2-(hydroxymethyl)-5-phenyl-L-norvaline + (3R)-3-hydroxy-2-(hydroxymethyl)-5-phenyl-L-norvaline
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455522
|
|
|
|
D-serine + H2O + methylene_blue <=> Hydroxypyruvate + NH3 + reduced_methylene_blue
|
1.4.99.6
D-arginine dehydrogenase
|
–
|
|
|
BRENDA:
BS260544
|
|
|
|
D-serine + (S)-Cbz-alaninal + H2O <=> (3S,4S)-4-[[(benzyloxy)carbonyl]amino]-3-hydroxy-2-(hydroxymethyl)-L-norvaline + (3R,4S)-4-[[(benzyloxy)carbonyl]amino]-3-hydroxy-2-(hydroxymethyl)-L-norvaline
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455532
|
|
|
|
D-serine + N-benzyloxycarbonyl-3-aminopropanal + H2O <=> (3S)-N6-[(benzyloxy)carbonyl]-3-hydroxy-2-(hydroxymethyl)-L-lysine + (3R)-N6-[(benzyloxy)carbonyl]-3-hydroxy-2-(hydroxymethyl)-L-lysine
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455530
|
|
|
|
D-serine + N-benzyloxycarbonyl-glycinal + H2O <=> (3S)-4-[[(benzyloxy)carbonyl]amino]-2'',3-dihydroxy-L-isovaline + (3R)-4-[[(benzyloxy)carbonyl]amino]-2'',3-dihydroxy-L-isovaline
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455529
|
|
|
|
D-serine + oxidized_acceptor + H2O <=> Hydroxypyruvate + NH3 + reduced_acceptor
|
1.4.5.1
D-amino acid dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS404909
|
|
|
|
D-serine + 4-hydroxybenzaldehyde + H2O <=> (2S,3S)-2-amino-3-hydroxy-2-(hydroxymethyl)-3-(4-hydroxyphenyl)propanoic_acid + (2S,3R)-2-amino-3-hydroxy-2-(hydroxymethyl)-3-(4-hydroxyphenyl)propanoic_acid
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455526
|
|
|
|
D-serine + 4-nitrobenzaldehyde + H2O <=> (2S,3S)-2-amino-3-hydroxy-2-(hydroxymethyl)-3-(4-nitrophenyl)propanoic_acid + (2S,3R)-2-amino-3-hydroxy-2-(hydroxymethyl)-3-(4-nitrophenyl)propanoic_acid
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455527
|
|
|
|
D-serine + phenylacetaldehyde + H2O <=> (3S)-2'',3-dihydroxy-4-phenyl-L-isovaline + (3R)-2'',3-dihydroxy-4-phenyl-L-isovaline
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455535
|
|
|
|
D-serine + oxidized_2,6-dichlorophenolindophenol + H2O <=> Hydroxypyruvate + NH3 + reduced_2,6-dichlorophenolindophenol
|
1.4.5.1
D-amino acid dehydrogenase (quinone)
1.4.99.6
D-arginine dehydrogenase
1.5.99.13
D-proline dehydrogenase
|
–
–
–
|
|
|
BRENDA:
BS404907
|
|
|
|
D-serine + 2-oxoadipate <=> Hydroxypyruvate + 2-Aminoadipate
|
2.6.1.74
cephalosporin-C transaminase
|
–
|
|
|
BRENDA:
BS356888
|
|
|
|
D-serine + 4-acetoxybenzaldehyde + H2O <=> (2S,3S)-3-[4-(acetyloxy)phenyl]-2-amino-3-hydroxy-2-(hydroxymethyl)propanoic_acid + (2S,3R)-3-[4-(acetyloxy)phenyl]-2-amino-3-hydroxy-2-(hydroxymethyl)propanoic_acid
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
|
|
BRENDA:
BS455525
|
|
|
|
D-serine <=> pyruvate + H2O
|
5.1.1.18
serine racemase
|
–
|
|
|
BRENDA:
BS379678
|
|
|
|
D-serine + NADP+ <=> 2-ammoniomalonate_semialdehyde + NADPH
|
1.1.1.276
serine 3-dehydrogenase (NADP+)
|
–
|
|
|
BRENDA:
BS355782
|
|
|
|
D-serine-phosphoethanolamine + H2O <=> D-serine + Phosphoethanolamine
|
3.1.4.13
serine-ethanolaminephosphate phosphodiesterase
|
–
|
|
|
BRENDA:
BS64707
|
|
|
|
Gly-D-Ser + H2O <=> glycine + D-serine
|
3.4.13.17
non-stereospecific dipeptidase
|
–
|
|
|
BRENDA:
BS64898
|
|
|
|
D-serine_methyl_ester + H2O <=> D-serine + methanol
|
3.1.1.43
alpha-amino-acid esterase
|
–
|
|
|
BRENDA:
BS64502
|
|
|
|
ATP + D-alanine + D-serine <=> ADP + D-Ala-D-Ser + D-Ala-D-Ala + D-seryl-D-serine
|
6.3.2.4
D-alanine---D-alanine ligase
|
–
|
|
|
BRENDA:
BS379287
|
|
|
|
ATP + D-serine <=> ADP + phosphate + D-seryl-D-serine
|
6.3.2.4
D-alanine---D-alanine ligase
|
–
|
|
|
BRENDA:
BS388021
|
|
|
|
ATP + gamma-Glu-L-Cys + D-serine <=> ADP + phosphate + gamma-Glu-L-Cys-D-Ser
|
6.3.2.3
glutathione synthase
|
–
|
|
|
BRENDA:
BS379334
|
|
|
|
ATP + D-serine <=> ADP + phosphate + D-Ala-D-Ser
|
6.3.2.4
D-alanine---D-alanine ligase
|
–
|
|
|
BRENDA:
BS369132
|
|
|
|
D-serine + ATP <=> ADP + D-seryl-D-serine
|
6.3.2.4
D-alanine---D-alanine ligase
|
–
|
|
|
BRENDA:
BS379676
|
|